Robust Regression Analysis of Copy Number Variation Data based on a Univariate Score
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چکیده
منابع مشابه
Robust Regression Analysis of Copy Number Variation Data based on a Univariate Score
MOTIVATION The discovery that copy number variants (CNVs) are widespread in the human genome has motivated development of numerous algorithms that attempt to detect CNVs from intensity data. However, all approaches are plagued by high false discovery rates. Further, because CNVs are characterized by two dimensions (length and intensity) it is unclear how to order called CNVs to prioritize exper...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2014
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0086272